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The bark of the sacred vine includes several alkaloids with gentle psychotropic properties, which might be also to blame for the brew’s purgative effects.textbooks.google.com/textbooks?id=b_z8CAAAQBAJ&pg=PT117&lpg=PT117&dq=%22one+of+the+essential+pillars+of+the+identity+of+the+Amazon+peoples%22&supply=bl&ots=uB9IFvR52C&sig=x3mmDODC4zJer61bw31dK3w